Characteristics of Amniotic Derived Stem Cells

  March 27th 2019    Blog

It’s a fact that human amniotic fluid cells have been utilized to diagnose prenatal conditions and check for chromosomal variations for a considerable length of time. As of late, though, specialists have found that amniotic derived stem cells can likewise be a great source of stem cells. Specialists at the Department of Development and Regeneration in Leuven, Belgium have recently unveiled in an article depicting the most secure and best cryopreservation techniques for these imperative cells for long term storage.
In spite of the fact that stem cells are additionally found in adults and umbilical cord blood, these have just restricted capacity to be changed into various sorts of tissue in the laboratory. Embryonic stem cells are not restricted in this manner and can possibly be transformed into any piece of the body. Notwithstanding, the embryos are damaged in the process making the research debatable. The scientists at Wake Forest, administered by Anthony Atala, see the new cells as an intermediate stage in the middle of embryonic and adult stem cells regarding their potential for changing into new cell types.
Though other groups have figured out how to grow particular cell types from amniotic cells, Professor Atala insists that their cells are entirely different from those found by other specialists as they seem to be ‘completely undifferentiated’ implying that, in principle, they can turn out to be any cell type found in the body. The new cells additionally demonstrate a few benefits over embryonic stem cells as they don’t appear to form tumors, a possible hazard when utilizing embryonic stem cells.
In the wake of growing the stem cells lines into new tissue forms, the group transplanted them into mice to see the impact in the body. The transplanted cells incorporated and produced the right chemicals, and bone precursor cells injected onto a ‘scaffold’ appeared to emulate ordinary bone formation.
The amniotic derived stem cells would be an immediate tissue match for the child from whom the encompassing fluid was extracted, however may likewise have a diminished possibility of rejection, contrasted with adult stem cells, as fetal cells will in general have lower immunogenicity to decrease the chance of the fetus being rejected by the mother. The amniotic derived stem cells lines seem to be steady in culture for extensive period of time and, as per Professor Atala, are easier to grow as compared to human embryonic stem cells.
Amniotic derived stem cells have been utilized to create pluripotent stem cells that are fundamentally the same as embryonic stem cells, without genetic manipulation, and without the ethical considerations embryonic cells convey (to sum up), they are encouraging source for future cell therapies.

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